Metabolic map about propionyl-CoA utilization

Video about oxiddation of fatty acids

Music about fatty acid oxidation

Dr. Ahern adapted the song When Johnny Comes Marching Home, turning it a song about the oxidation of fatty acids.

Download the music here

When Acids Get Oxidized

The fatty acids carried by
CoA, CoA
Are oxidized inside the
mi-to-chon-dri-ay
They get to there as you have seen
By hitching rides on carnitine
Then it goes away
When acids get oxidized

Electrons move through membranes, yes
It’s true, it’s true
They jump from complex I onto
Co-Q, Co-Q
The action can be quite intense
When building proton gradients
And its good for you
When acids get oxidized

The protons pass through complex V
You see, you see
They do this to make lots of
A-TP, TP
The mechanism you should know
Goes through the stages L-T-O
So there's energy
When acids get oxidized
.

Beta-oxidation rap

Video about the transport of fatty acids to the mitochondria

Here it is a video about the transport of fatty acids to the mitochondria, where they are degraded.

Metabolic maps about fatty acid oxidation

Transport of fatty acids into mitochondria…


Mitochondrial beta-oxidation…


Comparision between mitochondrial and peroxisomal beta-oxidation…

Oxidation of unsaturated fatty acids…

Omega-oxidation…

http://www.biocarta.com/genes/Metabolism.asp

Music about beta-oxidation

In 1883, William H. Hills composed the music There is a Tavern in the Town. Some years later (almost 100!), Dr. Baum re-wrote it, adapting it to beta-oxidation. Here goes the link for the download of the .mp3 file.

http://www.mediafire.com/?7gh93xfzy1fb814

Oxidation of fatty acids (main aspects)

Beta-oxidation
 - Type of metabolic pathway: catabolic
- Main goal: energy production through the degradation of fatty acids
- Subcellular localization: mitochondrial matrix
- Conditions required to occur: aerobic
- Number of biochemical reactions (per cycle): 4
- Energetic output (per cycle): +1 NADH e +1 FADH₂
- Final product (per cycle): 1 acetil-CoA