Music about the synthesis of fatty acids

Who could imagine that the song When Johnny Comes Marching Home could be converted in a song about the synthesis of fatty acids? Dr. Ahern, of course! :)

Download the music here

When Acids Are Synthesized

The 16 carbon fatty acid, palmitate
Gets all the carbons that it needs from acetate
Which citric acid helps release
From mitochondri - matrices
Oh a shuttle's great
When acids are synthesized

Carboxylase takes substrate and it puts within
Dioxy carbon carried on a biotin
CoA's all gain a quick release
Replaced by larger ACPs
And it all begins
When acids are synthesized

A malonate contributes to the growing chain
Two carbons seven times around again, again
For saturated acyl-ates
There's lots of N-A-DPH
That you must obtain
When acids are synthesized

Palmitic acid made this way all gets released
Desaturases act to make omega-threes
The finished products big and small
Form esters with a glycerol
So you get obese
When acids are synthesized
.

Video about fatty acid synthesis

Metabolic map of the transport of acetyl-CoA out from the mitochondria (fatty acid synthesis)

Here is a map on the metabolic process of sending the molecules of acetyl-CoA from the mitochondria (where they are predominantly formed) to the cytosol (where they are used for the synthesis of fatty acids).

http://www.biocarta.com/genes/Metabolism.asp

Music about fatty acid synthesis

The song Men of Harlech was an inspiration to Dr. Baum to create a song about the synthesis of fatty acids. Here is the link to this file:

http://www.mediafire.com/?ws41x73sc61oknd

Synthesis of fatty acids (main aspects)

Synthesis of fatty acids
- Type of metabolic pathway: anabolic
- Main goal: synthesis of fatty acids from acetyl-CoA
- Subcellular localization: cytosol
- Number of biochemical reactions (per cycle): 4
- Energetic outcome (per cycle): -2 NADPH and -1 ATP
- Final product (per cycle): fatty acid chain with two more carbons