Music about enzymes

Here it goes a link to download another Metabolic Melody from Dr. Ahern (www.davincipress.com/metabmelodies.html), this time about enzymes. It was base on the song Downtown.

http://www.mediafire.com/?w0gd96oo6ecpymg

Enzymes

Reactions alone

Energy peaks

Are what an enzyme defeats

In its catalysis

Enzymes

Transition state

Is what an enzyme does great

And you should all know this

Enzymes

Catalytic action won't run wild - don't get hysteric

Cells can throttle pathways with an enzyme allosteric

You know it's true

So when an effector fits

It will just rearrange

all the sub-u-nits

Inside an

ENZYME!

Flipping from R to T

ENZYME!

Slow catalytically

ENZYME!

No change in Delta G

(Enzyme, enzyme)

You should relax

When seeking out the Vmax though

There are many steps

Enzymes

Lineweaver Burk

Can save a scientist work

With just two intercepts

Enzymes

Plotting all the data from kinetic exploration

Let's you match a line into a best fitting equation

Here's what you do

Both axes are inverted then

You can determine Vmax and

Establish Km for your ENZYMES!

Sterically holding tight

ENZYMES!

Substrates positioned right

ENZYMES!

Inside the active site

Enzymes (Enzymes, enzymes, enzymes)

Could starve your cells to the bone

Thank God we all produce

Enzymes

Units arrange

To make the chemicals change

Because you always use

Enzymes

Sometimes mechanisms run like they are at the races

Witness the Kcat of the carbonic anhydrases

How do they work?

Inside of the active site

It just grabs onto a substrate

and squeezes it tight

In an

ENZYME!

CAT-al-y-sis

In an ENZYME!

V versus S

In an

ENZYME!

All of this working for you

(Enzyme, enzyme)