Thursday, October 6, 2011

Music about enzyme catalysis

This music is about enzyme catalysis and is an adaptation made by Dr. Ahern ( of the song Close to You.

My enzymes
Truly are inclined
To convert
Things they bind
Turn the key

How do cells
Regulate these roles?
Allo-ster-ic controls
Two forms, see
States R and T
Competing inhibition keeps
The substrates from the active site
They raise Km, but leave Vmax and shirk
While the non-competers bind elsewhere
And lift the plot made on Lineweaver-Burk

Other ways
Enzymes can be blocked
When things bind
Then get locked
Stuck not free
Tied to the key

Penicillin’s action stops
Peptidoglycan cross-links in
Bacterial cell walls in awesome ways
Beta lactam ring’s reactive site
Starts bonding with D-D-transpeptidase
So there are
Several enzyme states
Counteract-ing substrates
Now you see
Blocking the key
Have to be controlled
Some get slowed
Put on hold
It's sublime
How the enzymes
(slow) Cat-a-lyze
ahhhhhhhhhhhhhhhhhhh - cat-a-lyzeahhhhhhhhhhhhhhhhhhh - cata-
lyzeahhhhhhhhhhhhhhhhhhh - cat-a-lyze

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