The
dipole-dipole interaction, unlike the ionic bond (recently explained here in the
blog ... ) involves non ionizable functional groups, ie without total positive or negative charges. It involves regions with partial charges...
It is a
type of electrostatic interaction established between polar molecules, or at
least between polar regions of biomolecules. As explained on a previous post about
the concept of electronegativity, the presence of atoms with different
electronegativities in a specific region of a molecule, will lead to
inequalities in the distribution of the electronic cloud, which will, in turn, create regions with less electron density (and hence with partial positive
charges) and regions with higher electron density (and hence with partial
negative charges).
Thus, a
region with a partial positive charge tends to interact electrostatically with
a region of a partial negative charge, through a dipole-dipole bond.
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